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Fundamental Cellular Signaling Pathways The therapeutic efficacy of GLP-1 RAs stems from complex intracellular signaling cascades that operate across multiple organ systems through the GLP-1 receptor, a class B G protein-coupled receptor

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Vinu , Navarro J, Herrero-Cervera A, Garca-Cubas M, Andrs-Blasco I, Martnez-Hervs S, Real JT, Ascaso JF, Gonzlez-Navarro H: The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype